NBC

Are You There Vodka? It’s Me, Chelsea

Inspired by the book written by comedian and talk show host Chelsea Handler (E!’s “Chelsea Lately”), this sitcom follows bartender Chelsea (Laura Prepon) as she lives it up with her friends.

Awake

A detective can’t tell anymore if his days with his wife are complemented by a dream life with his dead son, or if it’s the other way around.

Bent

This romantic sitcom is about two people who are bent but definitely not broken. On the surface, Alex (Amanda Peet) and Pete (David Walton) couldn’t be more different. But neither can resist being attracted to what repels them the most.

Best Friends Forever

This comedy about friends who stick together, no matter the circumstances. After her husband files for divorce, Jessica (St. Clair) moves in with her best friend, Lennon (Parham), on the other side of the country.

The Biggest Loser

Jillian Michaels has moved on to other personal and professional ventures, making room for comely tennis star Anna Kournikova to join the team.

Chase

With an executive-producing roster led by entertainment wunderkind Jerry Bruckheimer and stocked with other veterans of the CSI franchise, The Mentalist, Without a Trace and Lost, it’s little surprise that Chase’s weekly fugitive hunts are as gripping and well-crafted as a good action movie.

Chuck

Chuck’s fifth and final season premieres Oct. 21 and moves to a new night on Fridays.

Community

The study group returns to Greendale Community College for a third season, this time studying biology.

Day One

Executive producer/writer Jesse Alexander (Heroes, Lost, Alias) is behind this series that tells the story of life on Earth following a global catastrophe that has devastated the world’s infrastructures. Beginning with the immediate aftermath of the cataclysmic event, an eclectic band of survivors strives to rebuild society.

The Event

NBC’s The Event is not so much a whodunit as a whatisit, as a stellar ensemble cast comes together to tell the story of an embattled U.S. president, a group of clandestine prisoners, and a confused everyman who gets caught up in a deadly conspiracy.

Free Agents (NBC)

Alex (Hank Azaria) and Helen (Kathryn Hahn) work together at a big-time corporate PR firm. After a night of drinking ends up with them in bed together, they have to decide where their relationship goes next.

Friends With Benefits

A group of single friends — a womanizer, a hopeless romantic, a straight-shooter, and two who just casually sleep together — try to navigate the complicated world of dating and the confusing line between friendship and romance.

Grimm

A Portland, Ore., detective discovers he is the latest in a line of “Grimm hunters,” people who can see the true face of monstrous creatures that storytellers like the Brothers Grimm tried to warn us about.

Heroes

New Faces: New guest stars include Robert Knepper (Prison Break), Dawn Olivieri, Ray Park (a.k.a. Darth Maul of Star Wars), [...]

The Jay Leno Show

Jay Leno returns with an hour-long talk show featuring former Tonight Show features and segments at an earlier time slot.

Law & Order: Los Angeles

The “Law & Order” franchise moves to Los Angeles as Skeet Ulrich and Corey Stoll play the detectives, and Alfred Molina and Terrence Howard play the prosecutors.

Law & Order: SVU

Where We Left Off: A shootout in the squad room left recurring character Sister Peg dead, and Stabler (Christopher Meloni) [...]

Law & Order

Where We Left Off: “The polls open in seven hours,” Assistant District Attorney Connie Rubirosa (Alana De La Garza) said [...]

Love Bites

An hourlong romantic comedy anthology series starring Becki Newton.

Mercy

Veronica is a nurse with more than her share of issues since she got back from Iraq. Why do life and love have to be this complicated?

The Office

Michael Scott (Steve Carell) has walked off into the sunset, but The Office will go on. In the season finale, Dunder Mifflin was interviewing candidates to replace Michael.

Outlaw

Jimmy Smits stars as Cyrus Garza, a right-wing Supreme Court justice who has an epiphany of sorts and steps down from the bench to right the wrongs of a corrupt legal profession that places personal gain over innocence and guilt.

Outsourced

American novelty company go-getter Todd has to teach his new employees after he’s reassigned to run a call center in India.

Parenthood

William Baldwin joins the cast as Adam’s (Peter Krause) boss, who will also be a possible love interest for Sarah (Lauren Graham). A new baby is also in the offing, but no word as to who will be expecting.

Parks and Recreation

Leslie Knope (Amy Poehler), an ambitious bureaucrat in the parks and recreation department, fights red tape to make life better for the citizens of Pawnee, Ind.

The Paul Reiser Show

It’s about what you do after you’ve gotten everything you’ve always wanted in life, then have to figure out what to do next. In this sitcom based on his real life, Reiser — who you might remember as that guy from that show — deals with just that scenario.

Perfect Couples

These three couples who are anything but perfect. There’s the carwreck couple who always seem to be throwing things or throwing themselves at one another; the know-it-alls who want to fix every relationship but their own; and the “average” couple, who are stuck in between.

The Playboy Club

1960s Chicago is the setting for this melodrama that follows the lives of people involved in the infamous Playboy Club, including an assorted group of businessmen, gangsters, and, of course, the Bunnies.

Prime Suspect

Jane Timoney brings her tenacity and investigative skill to NYPD homicide, but has to overcome the resentment of the old-boys’ network and earn their respect.

Rock Center With Brian Williams

NBC News’ first new primetime broadcast in nearly 20 years, this newsmagazine is led by anchor and managing editor Brian Williams, and will feature Harry Smith, Kate Snow, and other NBC anchors and correspondents, including Meredith Vieira, Dr. Nancy Snyderman, Richard Engel, Matt Lauer and Ann Curry.

Saturday Night Live

Alec Baldwin breaks the all-time “SNL” hosting record (he’s currently tied with Steve Martin at 15) when he hosts the Season 37 premiere on Sept. 24. “Mike & Molly” star Melissa McCarthy will host the season’s second episode.

School Pride

From “Curb Your Enthusiasm’s” Cheryl Hines and the makers of ABC’s feel-good hit “Extreme Makeover: Home Edition” comes this series that follows efforts to revitalize run-down schools.

The Sing-Off

Grammy-nominated singer/songwriter Sara Bareilles joins the vocal a cappella singing competition series for its third season as the third celebrity judge, alongside Ben Folds and Shawn Stockman. Nick Lachey is back to host the show, which returns in a weekly format with two-hour episodes.

30 Rock

Trauma

A group of EMTs helps people facing traumatic situations every day — but how do they cope with their own?

Undercovers

A creative collaboration between J.J. Abrams (Lost, Fringe) and Josh Reims (Brothers & Sisters, Felicity) creates a fractured dramedy about pair of former CIA agents turned caterers who are pulled back into covert activities when a friend from the agency turns up missing. This series may turn out to be the season’s best guilty pleasure.

Up All Night

Reagan (Christina Applegate) and Chris (Will Arnett) find their careers, their marriage and their good night’s sleep disrupted when they bring home their baby daughter.

Whitney

Even though Whitney (Whitney Cummings) and her boyfriend haven’t tied the knot, they’re starting to turn into an old married couple, and Whitney is determined to keep their relationship fresh.