What’s It All About? Continuing its unwavering commitment to breast cancer awareness, Lifetime has tapped superstar actresses Jennifer Aniston and Demi Moore, singer Alicia Keys and directors Patty Jenkins (Monster, The Killing) and Penelope Spheeris (Wayne’s World) to helm this anthology of five moving, funny and deeply interconnected short films about women and their loved ones forging their own paths in coping with the disease. Five boasts a staggering all-star cast that features Emmy nominee Tripplehorn (Big Love) as a doctor who lost her mother (Ginnifer Goodwin) to breast cancer as a child then discovers she has it herself; Academy Award^® nominee Patricia Clarkson (Pieces of April) as a quirky woman who throws herself a rollicking mock funeral and meets the love of her life; Fonesca (How I Met Your Mother) as a young exotic dancer unable to fathom life, love — or a career — without breasts; and Dawson (Sin City) as a conflicted career woman who struggles to accept her family’s support.

“Our hope with [Five] is to entertain, inform and inspire dialogue, research and prevention,” said Aniston in a statement released when she joined the project. “Otherwise, our goals are small. We want these films to move people and empower those affected by breast cancer to stand tall through this challenge, which impacts ALL of our lives, no matter who we are.”